Intensive Weight Loss Programs Might Help Reverse Diabetes






Type 2 diabetes has long been thought of as a chronic, irreversible disease. Some 25 million Americans are afflicted with the illness, which is associated with obesity and a sedentary lifestyle, as well as high blood pressure. Recent research demonstrated that gastric bypass surgery–a form of bariatric surgery that reduces the size of the stomach–can lead to at least temporary remission of type 2 diabetes in up to 62 percent of extremely obese adults. But can less drastic measures also help some people fight back the progressive disease?A new randomized controlled trial found that intensive weight loss programs can also increase the odds that overweight adults with type 2 diabetes will see at least partial remission. The findings were published online December 18 in JAMA, The Journal of the American Medical Association. “The increasing worldwide prevalence of type 2 diabetes, along with its wide-ranging complications, has led to hopes that the disease can be reversed or prevented,” wrote the authors of the new paper, led by Edward Gregg of the Centers for Disease Control and Prevention.The study tracked 4,503 overweight adults with type 2 diabetes for four years. About half of the subjects received basic diabetes support and education (including three sessions per year that covered diet, physical activity and support). The other half received more intensive lifestyle-intervention assistance. This second group received weekly individual and group counseling for six months, followed by three-sessions each month for the next six months, and refresher group sessions and individual contact for the subsequent three years. The interventions aimed to help individuals limit daily calories to 1,200 to 1,800–in particular by reducing saturated fat intake–and to help them get the recommended 175 minutes per week of physical activity.After two years about one in 11 adults in the intervention group experienced at least partial remission of their diabetes, meaning that a patient’s blood sugar levels reverted to below diabetes diagnosis levels without medication. Only about one in 60 in the control group, which received only basic support and education, saw any remission after two years. The findings suggest that “partial remission, defined by a transition to prediabetic or normal glucose levels without drug treatment for a specific period, is an obtainable goal for some patients with type 2 diabetes,” the researchers noted.The improvement, however, was not indefinite for everyone. After four years, only about one in 30 people in the intervention group were still seeing an improvement in their condition. Researchers think that regaining weight and falling behind on diet and physical activity goals increase the risk that people will return to a diabetic state.About one in 75 in the intervention group saw complete remission of their diabetes, in which glucose levels returned to normal without medication.The study did not find, however, that individuals in the lifestyle intervention group had lower risks for heart trouble, stroke or death than did those in the control group. “This recently led the National Institutes of Health to halt the [trial],” noted David Arterburn, of Group Health Research Institute in Seattle, and Patrick O’Connor, of HealthPartners Institute for Education and Research in Minneapolis, in an essay in the same issue of JAMA. Similar results have come out of studies looking at more intensive medical treatment of diabetes. “A more potent intervention–bariatric surgery–already appears to achieve what intensive medical and lifestyle interventions cannot: reducing cardiovascular events and mortality rates among severely obese patients with type 2 diabetes,” they noted.As with any disease, however, prevention is the best strategy. “The disappointing results of recent trials of intensive lifestyle and medical management in patients with existing type 2 diabetes also underscore the need to more aggressively pursue primary prevention of diabetes,” Arterburn and O’Connor noted. One recent study found that compared with no treatment at all, lifestyle interventions reduced the onset of type 2 diabetes by 58 percent in people with pre-diabetes (and the medication metformin reduced the onset rate by 31 percent). Bariatric surgery seemed to reduce the onset of diabetes in obese patients by 83 percent, Arterburn and O’Connor pointed out in their essay.For people who already have diabetes, however, those who are still in the early stages and those with the biggest weight loss and/or fitness improvement had the best odds for beating the disease. And even if lifestyle interventions aren’t capable of dialing back the disease entirely, any reduction–whether through lifestyle or other changes-in the need for medication and in medical complications due to diabetes can be considered an improvement in managing the disease, which already costs the U.S. health system $ 116 billion each year and is estimated to affect 50 million Americans by 2050.


Follow Scientific American on Twitter @SciAm and @SciamBlogs.Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.
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Rush to boost safety sparks flurry of ideas


(Reuters) - They began calling on Friday morning, even before confirmation of the death toll at Sandy Hook Elementary. Principals, district administrators, school police chiefs all asked the same pleading questions: What can we do? How do we stop this? How can we keep our children safe?


Michael Dorn, phone to his ear until 2 a.m., gave them all the same advice: Slow down.


Every horrific school shooting sets off a rush to bolster security, and Dorn, a widely respected school safety consultant, says he has seen hundreds of millions of dollars wasted in the frenzy to upgrade.


Principals spend lavishly on emergency response software, not realizing how impractical it is to fumble with a log-in during a crisis. Districts buy pricey metal detectors, only to switch them off because they cannot afford to deploy staff to do pat-downs and search book bags.


"People are frightened. They're trying so hard," said Dorn, a former schools police chief who runs the nonprofit consulting network Safe Havens International in Macon, Georgia. "But you want to build something that will last decades. Focus on making quality improvements rather than doing it quickly."


The horrific toll in Newtown has prompted administrators across the U.S. to reassess their safety protocols. Some have found obvious deficiencies that will take money to fix, such as classroom doors that don't lock. Bu t in many cases, security experts say districts can strengthen safety on campus without big spending.


In a survey conducted by the American Association of School Administrators in 2009 -- the 10th anniversary of the Columbine High School shootings -- fully a third of educators admitted they sometimes propped open doors to their schools, potentially giving intruders easy access. And almost 40 percent acknowledged they weren't training staff adequately in emergency response.


School safety consultants said such lapses remained common until the Newtown tragedy snapped administrators out of their complacency. "We tend to let our guard down as memories fade," said Paul Timm, president of RETA Security Inc, a consulting firm in Lemont, Illinois.


He and others said schools could greatly improve safety with a series of inexpensive measures: Keep all exterior doors shut and locked. Equip recess monitors with walkie-talkies to report signs of trouble. Regularly review emergency plans and practice for a variety of scenarios, not just an active shooter. Train all adults on campus to recognize behavior patterns that could indicate that a student is planning mischief or malice.


Hundreds of school districts and colleges across the U.S. have also adopted a more controversial approach to safety: teaching staff -- and students -- to fight back in the face of danger.


The ALICE protocol, developed a decade ago by a former police officer in response to a series of school shootings, rejects as inadequate the traditional response to an armed intruder, which prompts teachers and students to lock themselves in their classroom, turn out the lights and hide as best they can.


Greg Crane, the retired police officer who developed ALICE, says rather than fall back on that response, students and teachers must develop the confidence that allows them to think on their feet.


If they can escape the building quickly, through a window perhaps, why huddle in a darkened classroom? And if an intruder enters the classroom, why remain passive; why not run around, scream, throw books and desks at the gunman, even try to tackle him, Crane asks.


"If a predator tried to snatch a child off the street, what part of our advice is for him to remain quiet, static, passive?" Crane asked. "We want you throwing things, yelling, trying to get out of there," he said. The same should hold in a classroom, he said, arguing that even 5- and 6-year-olds can cause enough distraction to confuse a gunman and perhaps buy a few minutes for escape.


"Chaos is not a bad thing," Crane said. "We want to see chaos. That makes it very difficult for the shooter to operate."


The ALICE program -- it stands for Alert, Lockdown, Inform, Counter, Evacuate -- has sparked concern in some communities, with parents protesting that terrified children can't be asked to confront crazed gunmen or make snap decisions about escape routes.


But Crane said his company, Response Options, which is based in Burleson, Texas, has been flooded with calls since Friday from officials eager to sign up for his $400 training workshop, which prepares participants to teach ALICE to students and teachers in their communities.


While the tragedy at Sandy Hook focused attention on the danger of armed intruders, safety consultants cautioned that schools must also remain vigilant about internal threats from students who may feel alienated or may be struggling with mental illness.


"The ultimate in safety is caring about one another and kids trusting you with information," said Bill Bond, a security consultant with the National Association of Secondary School Principals.


Bond was the principal at Heath High School in West Paducah, Kentucky, in 1997, when a student opened fire on a morning prayer circle, killing three girls. He advocates programs that connect children with adult mentors.


Such connections are harder to maintain in an era of tight budgets, however. There is just one school counselor for every 471 students in the U.S.; a few years ago, the ratio was 1 to 457, according to the American School Counselor Association. Faced with tight budgets, some districts have asked every adult connected with the school, including bus drivers, custodians and cafeteria workers, to pitch in with mentoring and monitoring kids.


"People want to be able to say, if we just do X, Y and Z in every school in America, we'll stop these," said Dorn, the security consultant in Georgia. There is no such solution, he said. Each school, and each threat, is too different.


But Dorn said he understands why the school officials who call him up are so eager to do something, anything, at once. "I have a 4-year-old. I took him to school this morning," Dorn said. "I understand the fear." (Reporting By Stephanie Simon. Editing by Douglas Royalty)



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N. Korea displays Kim Jong Il a year after death






PYONGYANG, North Korea (AP) — North Korea unveiled the embalmed body of Kim Jong Il, still in his trademark khaki jumpsuit, on the anniversary of his death Monday as mourning mixed with pride over a recent satellite launch that was a long-held goal of the late authoritarian leader.


Kim lies in state a few floors below his father, national founder Kim Il Sung, in the Kumsusan mausoleum, the cavernous former presidential palace. Kim Jong Il is presented lying beneath a red blanket, a spotlight shining on his face in a room suffused in red.






Wails echoed through the chilly hall as a group of North Korean women sobbed into the sashes of their traditional Korean dresses as they bowed before his body. The hall bearing the glass coffin was opened to select visitors — including The Associated Press — for the first time since his death.


North Korea also unveiled Kim’s yacht and his armored train carriage, where he is said to have died. Among the personal belongings featured in the mausoleum are the parka, sunglasses and pointy platform shoes he famously wore in the last decades of his life. A MacBook Pro lay open on his desk.


North Koreans paid homage to Kim and basked in the success of last week’s launch of a long-range rocket that sent a satellite named after him to space.


The launch, condemned in many other capitals as a violation of bans against developing its missile technology, was portrayed not only as a gift to Kim Jong Il but also as proof that his young son, Kim Jong Un, has the strength and vision to lead the country.


The elder Kim died last Dec. 17 from a heart attack while traveling on his train. His death was followed by scenes of North Koreans dramatically wailing in the streets of Pyongyang, and of the 20-something son leading ranks of uniformed and gray-haired officials through funeral and mourning rites.


The mood in the capital was decidedly more upbeat a year later, with some of the euphoria carrying over from last Wednesday’s launch. The satellite bears one of Kim Jong Il’s nicknames, Kwangmyongsong, or “Lode Star,” a moniker given to him at birth according to the official lore.


Cameras were not allowed inside the mausoleum, and state media did not release any images of Kim Jong Il’s body.


With the death anniversary came a hint that Kim Jong Un himself might soon be a father.


His wife, Ri Sol Ju, was seen on state TV with what appeared to be a baby bump as she walked slowly next to her husband at the mausoleum, where they bowed to statues of Kim’s father and grandfather.


There is no official word from Pyongyang about a pregnancy. In addition, Ri is shown wearing a billowing traditional Korean dress in black that makes it difficult to know for sure.


North Koreans are reluctant to discuss details of the Kim family that have not been released by the state. Still there are rumors even in Pyongyang about whether the country’s first couple is expecting.


To honor Kim’s father, North Koreans stopped in their tracks at midday and bowed their heads as the national flag fluttered at half-staff along streets and from buildings.


Pyongyang construction workers took off their yellow hard hats and bowed at the waist as sirens wailed across the city for three minutes.


Tens of thousands of North Koreans gathered in the frigid plaza outside, newly transformed into a public park with lawns and pergolas. Geese flew past snow-tinged firs and swans dallied in the partly frozen moat that rings the vast complex in Pyongyang’s outskirts.


“Just when we were thinking how best to uphold our general, he passed away,” Kim Jong Ran said at the plaza. “But we upheld leader Kim Jong Un. … We regained our strength and we are filled with determination to work harder for our country.”


Speaking outside the mausoleum, renamed the Kumsusan Palace of the Sun, the military’s top political officer, Choe Ryong Hae, said North Korea should be proud of the satellite, calling it “a political event with great significance in the history of Korea and humanity.”


Much of the rest of the world, however, was swift in condemning the launch, which was seen by the United States and other nations as a thinly disguised cover for testing missile technology that could someday be used for a nuclear warhead.


The test, which the U.N. Security Council said violated a ban on launches using ballistic missile technology, underlined Kim Jong Un’s determination to continue carrying out his father’s hardline policies even if they draw international condemnation.


Washington said Monday it has no option but to seek to isolate Pyongyang further.


“What’s left to us is to continue to increase pressure on the North Korean regime and we are looking at how to best to do that, both bilaterally and with our partners going forward until they (North Korea) get the message. We are going to further isolate this regime,” U.S. State Department spokeswoman Victoria Nuland said.


Some outside experts worry that Pyongyang’s next move will be to press ahead with a nuclear test in the coming weeks, a step toward building a warhead small enough to be carried by a long-range missile.


Despite inviting further isolation for his impoverished nation and the threat of stiffer sanctions, Kim Jong Un won national prestige and clout by going ahead with the rocket launch.


At a memorial service on Sunday, North Korea’s top leadership not only eulogized Kim Jong Il, but also praised his son. Kim Yong Nam, president of the Presidium of North Korea’s parliament, called the launch a “shining victory” and an emblem of the promise that lies ahead with Kim Jong Un in power.


The rocket’s success also fits neatly into the narrative of Kim Jong Il’s death. Even before he died, the father had laid the groundwork for his son to inherit a government focused on science, technology and improving the economy. And his pursuit of nuclear weapons and the policy of putting the military ahead of all other national concerns have also carried into Kim Jong Un’s reign.


In a sign of the rocket launch’s importance, Kim Jong Un invited the scientists in charge of it to attend the mourning rites in Pyongyang, according to state media.


The reopening of the mausoleum on the anniversary of the leader’s death follows tradition. Kumsusan, the palace where his father, Kim Il Sung, served as president, was reopened as a mausoleum on the anniversary of his death in 1994.


___


Associated Press writers Hyung-jin Kim in Seoul, South Korea, and Matthew Pennington in Washington contributed to this report. Follow Jean Lee, AP’s bureau chief for Pyongyang and Seoul, at www.twitter.com/newsjean.


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Participant Media plans cable TV network targeting millenials






LOS ANGELES (Reuters) – Entertainment company Participant Media, one of the backers of the hit historical drama “Lincoln”, will launch a cable TV network next summer with programming that focuses on social issues of interest to the millenials generation of teens and young adults.


The channel’s original programming, films and documentaries will be aimed at viewers age 18 to 34 in the large demographic group known as millenials, Participant Media CEO Jim Berk said in an interview on Monday.






Millenials are particularly interested in the type of content that Participant produces about social issues, Berk said. The studio’s credits include the current release “Lincoln”, about President Abraham Lincoln‘s push to ban slavery, last year’s civil rights drama “The Help” and Al Gore climate change documentary “An Inconvenient Truth”.


Participant Media is creating the new network by purchasing two existing cable channels, The Documentary Channel and Halogen TV. After those networks are combined and rebranded, the new channel will reach an estimated 40 million of the more than 100 million U.S. pay-TV subscribers.


The company, founded by billionaire and former eBay Inc President Jeff Skoll with the aim of producing entertaining content that inspires social change, interacts regularly with more than 2.5 million people through social media, local movie screenings and its Takepart.com website, Berk said.


The challenge for Participant will be to sign up additional pay-TV distributors and win viewership in a crowded media landscape. The company is privately held and is not part of a large media conglomerate.


“We have the funding necessary to take a very long-term view, and to spend what we need to spend in terms of programming,” Berk said.


The mainstay of the network’s lineup will be original programming from a variety of genres, said Evan Shapiro, a Participant executive who will run the new network.


The company is developing programming with established Hollywood names including former MTV President Brian Graden, “Inconvenient Truth” director Davis Guggenheim and documentary filmmaker Morgan Spurlock.


Participant also hopes to work with pay-TV distributors to make the channel’s content available on mobile devices such as smartphones and tablets, to meet the viewing patterns of younger audiences, Shapiro said.


(Reporting By Lisa Richwine; Editing by Edmund Klamann)


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Asocian la cobertura oftalmológica con una mejor salud visual






17 dic (Reuters) – Las personas de entre 40 y 65 años con


cobertura de atención oftalmológica eran dos veces más propensas






a haber concurrido a un oculista durante los 12 meses previos y


tenían mejor capacidad para leer materiales impresos, señalan


investigadores.


“El estudio demuestra que la cobertura oftalmológica aumenta


la posibilidad de consultar a un oculista y que una consulta el


año anterior está asociada con un mejor estado de salud visual”,


resumen los autores en la revista Archives of Ophthalmology.


El equipo de Yi-Jhen Li, de University of South Carolina,


Columbia, recuerda que se estima que para 2020 habrá más de 5,6


millones de estadounidenses con una enfermedad ocular asociada


con la edad que puede causar ceguera.


Pero agrega que la disminución visual permanente por alguna


de esas causas, como el glaucoma y las cataratas, se puede


demorar con detección temprana y tratamiento.


“Los queremos de este lado de la puerta. Si eso ocurre,


ellos recibirán lo que necesitan”, dijo John Crews, investigador


de los CDC, Atlanta, y que no participó del estudio. “El


problema desde la salud pública es ‘¿qué le impide a la


población acceder a la atención?’”.


El equipo de Li utilizó los resultados de una encuesta del


2008 a 27.152 personas de ocho estados de Estados Unidos; 11.541


(43 por ciento) de ellas no tenía cobertura oftalmológica.


El 64 por ciento de las 15.611 personas con cobertura había


consultado a un oftalmólogo el año anterior, comparado con el 45


por ciento de los encuestados sin cobertura.


Tras considerar ciertos factores (edad, sexo y etnia), los


autores observaron que los participantes con buena salud que


tenían cobertura oftalmológica eran un 24 por ciento más


propensos a decir que podían reconocer a sus amigos en la vereda


de enfrente y que eran un 34 por ciento más propensos a decir


que podían leer material impreso sin inconvenientes, que


aquellos sin cobertura.


La diferencia fue aún mayor en un subgrupo con enfermedades


oculares comunes (glaucoma, cataratas o degeneración macular


asociada con la edad): aquellos con cobertura oftalmológica eran


un 37 por ciento más propensos a poder leer y un 45 por ciento


más propensos a reconocer a un amigo de lejos.


Tanto en la población general como en la población con


enfermedades oculares, los que habían consultado a un médico


durante el año anterior eran más propensos a tener mejor visión.


El equipo, que no estuvo disponible para esta nota, escribe


que el grupo etario en el que se concentró es muy joven para


recibir cobertura de Medicare, pero tiene “alto riesgo de


padecer enfermedades oculares que producen una disminución


visual gradual que se puede prevenir”.


Agrega que éste es el primer estudio del equipo sobre cómo


la cobertura oftalmológica versus la cobertura general influye


en la frecuencia de la consulta oftalmológica de este segmento


etario.


Mientras que el 85 por ciento de la muestra estudiada tenía


cobertura de salud, sólo el 68 por ciento de ese subgrupo tenía


cobertura oftalmológica. Para el equipo, el estudio indica que


la cobertura oftalmológica, y no el seguro de salud general, es


lo que determina no sólo si la población concurre al oculista,


sino también la calidad visual percibida.


La Academia Estadounidense de Oftalmología considera que los


adultos deben concurrir al oftalmólogo cada dos o cuatro años y


recomienda que los mayores de 65 lo hagan cada uno o dos años.


FUENTE: Archives of Ophthalmology, online 10 de diciembre


del 2012.


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Fate of massacre site can help healing


AURORA, Colo. (AP) — As Newtown, Conn., grieves the deadly mass shooting at Sandy Hook Elementary School, victims' families and residents will eventually have to decide what to do with the building and how to memorialize the fallen.


Will they decide to demolish the school where authorities say Adam Lanza killed 20 children and six adults before killing himself? Or just the parts where he opened fire? Will there be a memorial on school grounds, or in town? Or both?


Whatever they choose, it will give them a measure of control over a situation in which they have had very little, said Dr. Louis Kraus, chief of child and adolescent psychiatry at Rush University Medical Center in Chicago.


"To be able to have some control and say in that process I think is going to be very important" to the healing process, he said.


Here's a look at what communities that have faced deadly mass shootings have done:


— After a white supremacist opened fire in a Sikh temple in Oak Creek, Wis., in August, killing six people and injuring four, temple officials held a purifying ceremony and removed bloodstained carpeting, repaired shattered windows and painted over gunfire-scarred walls.


But they left one reminder of the violence — a dime-size bullet hole in the door jamb leading to the prayer room. The hole is now marked with a small gold plate engraved with "We Are One. 8-5-12."


"It frames the wound," Pardeep Kaleka, son of former temple president Satwant Singh Kaleka, who died in the massacre, said recently. "The wound of our community, the wound of our family, the wound of our society."


— After a gunman killed 12 people at a midnight showing of the Batman movie in Aurora, Colo., more than 70 percent of the 6,300 people who responded to an online survey wanted the theater reopened.


A memorial that sprang up near the theater is gone but a new sign offers sympathy to those suffering from the nation's latest mass shooting —"Newtown, CT We feel your pain."


— In Norway, extensive remodeling is planned on the small island of Utoya, where 69 people, more than half of them teenagers attending summer camp, were killed by a far-right gunman in 2011.


Utoya's main building, a cafeteria where 13 of the victims were shot to death, will be torn down and replaced by a cluster of new buildings surrounding a square, creating the feel of a "small village," project manager Joergen Frydnes said.


The idea is to bring back the positive atmosphere that characterized Utoya before the tragedy, he said. There was no summer camp this year and it's unclear when the left-wing youth group will be back at Utoya for what used to be its annual highlight.


Frydnes said it will happen, eventually.


— At Virginia Tech, the scene of the worst mass shooting in modern U.S. history, a classroom building where a student gunman killed 30 people in April 2007 is now home to the Center for Peace Studies and Violence Prevention.


A dormitory where the two other students were killed has been turned into a residential college. The gunman killed himself.


As at many other scenes of mass shootings, a memorial was created on the campus' main lawn recreating the 32 stones — one for each person killed — placed there in the hours after tragedy.


— In Pennsylvania, an Amish community quickly decided that removing a schoolhouse where five girls were killed and five others were wounded in October 2006 by a gunman would be the best way to help bring resolution, mainly out of sensitivity to their children.


Ten days after the shooting, heavy machinery moved in before dawn to demolish the West Nickel Mines Amish School, making the site indistinguishable from the surrounding pasture.


New Hope Amish School, its replacement with added security features, was built a few hundred yards away and opened April 2, 2007 — six months to the day after the massacre.


— After a man killed 16 children and a teacher at a primary school gymnasium in Dunblane, Scotland, before turning the gun on himself, authorities demolished the gym.


The site of the gym is now a small garden that includes a plaque with the names of all the victims, most of whom were aged 5. A new gym was built on the school grounds.


Two miles from the school, on the outskirts of the town, is a community center built after a vote on how to spend the money donated from well-wishers around the world.


On the night of the Newtown shooting, some people came to the center and lit candles, said Stewart Prodger, a trustee of the charity that runs the center.


— After two students went on a deadly rampage at Columbine High School in Littleton, Colo., in April 1999, students finished the year at another school. Columbine reopened in time for the following school year after extensive repairs.


"The intent of the school district is to put this back as a high school," Jack Swanzy, lead architect on the refurbishing project, said at the time. "We don't want to make it a shrine to the tragedy."


School district officials originally considered remodeling and reopening the second-floor library, where most of the students were killed, but parents objected and asked that it be demolished and replaced.


The district eventually agreed and the old library, which sat above the school cafeteria, was removed and the space converted into an atrium.


A memorial to those killed — 12 students and a teacher — opened years later on a hill above the school. The broad oval sunken into the rolling terrain still attracts people.


On Friday, after the Newtown shooting, Amber Essman, 24, made her first visit. She was in grade school at the time of the shooting and had been hesitant to visit before because of the emotions it would bring up.


She wanted to pay belated respects to those killed at Columbine and provide some comfort to their families. "They need comfort and peace today in addition to the families in Connecticut that have been affected," she said.


___


Associated Press writers Karl Ritter in Stockholm, Dinesh Ramde in Milwaukee, Michael Felberbaum in Richmond, Va., Mark Scolforo in Harrisburg, Pa., and Ben McConville in Edinburgh, Scotland, contributed to this report.


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Egyptians hand Islamists narrow win in constitution vote






CAIRO (Reuters) – Egyptians voted in favor of a constitution shaped by Islamists but opposed by other groups who fear it will divide the Arab world’s biggest nation, officials in rival camps said on Sunday after the first round of a two-stage referendum.


Next week’s second round is likely to give another “yes” vote as it includes districts seen as more sympathetic towards Islamists, analysts say, meaning the constitution would be approved.






But the narrow win so far gives Islamist President Mohamed Mursi only limited grounds for celebration by showing the wide rifts in a country where he needs to build a consensus for tough economic reforms.


The Muslim Brotherhood‘s party, which propelled Mursi to office in a June election, said 56.5 percent backed the text. Official results are not expected until after the next round.


While an opposition official conceded the “yes” camp appeared to have won the first round, the opposition National Salvation Front said in a statement that voting abuses meant a rerun was needed – although it did not explicitly challenge the Brotherhood‘s vote tally.


Rights groups reported abuses such as polling stations opening late, officials telling people how to vote and bribery. They also criticized widespread religious campaigning which portrayed “no” voters as heretics.


A joint statement by seven human rights groups urged the referendum’s organizers “to avoid these mistakes in the second stage of the referendum and to restage the first phase again”.


Mursi and his backers say the constitution is vital to move Egypt’s democratic transition forward. Opponents say the basic law is too Islamist and tramples on minority rights, including those of Christians who make up 10 percent of the population.


The build-up to Saturday’s vote was marred by deadly protests. Demonstrations erupted when Mursi awarded himself extra powers on November 22 and then fast-tracked the constitution through an assembly dominated by his Islamist allies.


However, the vote passed off calmly with long queues in Cairo and several other places, though unofficial tallies indicated turnout was around a third of the 26 million people eligible to vote this time. The vote was staggered because many judges needed to oversee polling staged a boycott in protest.


The opposition had said the vote should not have been held given the violent protests. Foreign governments are watching closely how the Islamists, long viewed warily in the West, handle themselves in power.


“It’s wrong to have a vote or referendum with the country in the state it is – blood and killings, and no security,” said Emad Sobhy, a voter who lives in Cairo. “Holding a referendum with the country as it is cannot give you a proper result.”


INCREASINGLY DIVIDED


As polls closed, Islamists attacked the offices of the newspaper of the liberal Wafd party, part of the opposition National Salvation Front coalition that pushed for a “no” vote.


“The referendum was 56.5 percent for the ‘yes’ vote,” a senior official in the Brotherhood’s Freedom and Justice Party operations room set up to monitor voting told Reuters.


The Brotherhood and its party had representatives at polling stations across the 10 areas, including Cairo, in this round. The official, who asked not to be identified, said the tally was based on counts from more than 99 percent of polling stations.


“The nation is increasingly divided and the pillars of state are swaying,” opposition politician Mohamed ElBaradei wrote on Twitter. “Poverty and illiteracy are fertile grounds for trading with religion. The level of awareness is rising fast.”


One opposition official also told Reuters the vote appeared to have gone in favor of Islamists who backed the constitution.


The opposition initially said its exit polls indicated the “no” camp would win comfortably, but officials changed tack during the night. One opposition official said in the early hours of Sunday that it would be “very close”.


A narrow loss could still hearten leftists, socialists, Christians and more liberal-minded Muslims who make up the disparate opposition, which has been beaten in two elections since Hosni Mubarak was overthrown last year.


They were drawn together to oppose what they saw as a power grab by Mursi as he pushed through the constitution. The National Salvation Front includes prominent figures such as ElBaradei, former Arab League chief Amr Moussa and firebrand leftist Hamdeen Sabahy.


If the constitution is approved, a parliamentary election will follow early next year.


DEADLY VIOLENCE


Analysts question whether the opposition group will keep together until the parliamentary election. The Islamist-dominated lower house of parliament elected earlier this year was dissolved based on a court order in June.


Violence in Cairo and other cities has plagued the run-up to the referendum. At least eight people were killed when rival camps clashed during demonstrations outside the presidential palace earlier this month.


In order to pass, the constitution must be approved by more than 50 percent of those casting ballots. There are 51 million eligible voters in the nation of 83 million.


Islamists have been counting on their disciplined ranks of supporters and on Egyptians desperate for an end to turmoil that has hammered the economy and sent Egypt’s pound to eight-year lows against the dollar.


The army deployed about 120,000 troops and 6,000 tanks and armored vehicles to protect polling stations and other government buildings. While the military backed Mubarak and his predecessors, it has not intervened in the present crisis.


(Additional reporting Yasmin Saleh and Marwa Awad; Writing by Edmund Blair and Giles Elgood; Editing by Tom Pfeiffer)


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Springsteen, Gaga join Stones; Newtown noted






NEW YORK (AP) — Only at a Rolling Stones concert could appearances by Bruce Springsteen and Lady Gaga seem almost like afterthoughts.


Those superstars and other top acts including the Black Keys and John Mayer jammed with the Stones on Saturday night, winding down a series of concerts celebrating the 50th year of rock’s most enduring band (the occasion was also marked by a pay-per-view special).






The Boss rocked out with the band on out “Tumbling Dice”; Gaga matched Mick Jagger shimmy-for-shimmy on “Gimme Shelter”; the Black Keys joined on “Who Do You Love,” and John Mayer and Gary Clark Jr. showed their considerable guitar chops alongside Keith Richards and Ronnie Wood on “Goin’ Down.”


But the Stones would not be upstaged. While the sold-out crowd roared with each special guest, it was the aging but dynamic foursome that generated the most excitement of the night, as they put new energy into their decades-old catalog of hits, including “It’s Only Rock ‘N Roll (But I Like It),” ”Start Me Up,” ”Brown Sugar,” ”Sympathy for the Devil” and more.


The band took a moment to acknowledge the shooting deaths of 20 children and six adults at an elementary school Friday in Newtown, Conn. “We just wanted to send our love and condolences to all the people who lost loved ones in the tragedy in Connecticut,” Jagger early on in the concert as the audience applauded. Jagger noted the entire world was feeling the pain of the stunned nation.


But it was the only somber moment in an a frenetic show that showed why the Stones are considered by many to be the greatest rock band, and belied the much-discussed advanced age of the group’s lineup (their ages range between 65 and 71).


Jagger himself poked fun at the senior citizen status of the band and their fans; speaking of the pay-per-view crowd at home, he joked: “Some of you have got your grandchildren watching you.”


But few acts in their so-called prime would have been able to match the energy the Stones radiated onstage. The group had the crowd on its feet for the entire show as Jagger gyrated across the stage, his voice in top form. Both Wood and Richards dazzled on guitar (Richards got a raucous, sustained ovation as he took over vocals on two songs). And Charlie Watts kept the beat strong on the drums.


Before performing in London together late last month for the first of the concerts, the Stones hadn’t performed in concert together since 2007. Going into these shows, there was some speculation that Saturday’s concert, held at the Prudential Center, might be their last.


Earlier in the evening, Jagger teased that the concert might signal the end: “This could be the last time; I don’t know,” he said. But by the end of the evening, it seemed clear that the question was not when the Stones would return, but when.


“This is the last show of our anniversary tour, and we hope to see you all again soon,” Jagger said.


Perhaps the night’s most special guest was Mick Taylor, the former Stones guitarist who was part of some of their biggest moments from 1969 to 1975, when he left the group. He rejoined his band mates (and the man who replaced him, Wood) onstage for a powerful performance of “Midnight Rambler”.


At the concert’s end, while other special guests gave their final bows and left the stage, Jagger motioned for Taylor to stay, and the five took their final bow together.


___


Nekesa Mumbi Moody is the AP’s Global Entertainment & Lifestyles Editor. Follow her at http://twitter.com/nekesamumbi


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Boehner opens door to tax hikes, shifts U.S. fiscal cliff talks






WASHINGTON (Reuters) – U.S. House of Representatives Speaker John Boehner‘s offer to accept a tax rate increase for the wealthiest Americans knocks down a key Republican road block to a deal resolving the year-end “fiscal cliff.”


The question now boils down to what President Barack Obama offers in return. Such major questions, still unanswered so close to the end of the year suggest, however, that no spending and tax agreement is imminent.






A source familiar with the Obama-Boehner talks confirmed that Boehner proposed extending low tax rates for everyone who has less than $ 1 million in net annual income, meaning tax rates would rise on all above that line.


Under current law, the 35 percent top tax rate is scheduled to expire on January 1, and would automatically go to 39.6 percent. Boehner’s proposal would allow that rate to rise as scheduled at a threshold of $ 1 million – putting it back to where it was during the Clinton administration.


The White House has not accepted the proposal and the source could not confirm any additional talks were held on Sunday between Obama and Boehner.


With just over two weeks before the fiscal cliff’s $ 600 billion in automatic tax hikes and spending cuts are triggered, threatening a new recession, there is little time to craft a comprehensive deal that will satisfy both Democrats and Republicans.


Until the latest Republican offer, made on Friday, Boehner had insisted on extending all of the Bush era’s lower tax rates, resisting Obama’s demand to let the marginal rates rise on income above $ 250,000. A rising chorus of business executives also had urged Republicans to agree to this.


Some lawmakers and congressional aides had predicted that Republicans, once serious negotiations began, might try to raise the $ 250,000 threshold, say to $ 500,000 or $ 1 million. They also speculated that Republicans, if forced into a tax rate hike on the upper-income groups, might seek a smaller increase, say to around 37 percent.


Although the White House has not accepted Boehner’s gambit, it could push negotiations away from entrenched, ideological positions.


“Boehner has now accepted the premise of higher rates. So now we’re just arguing over details. I think it’s a significant step,” said Greg Valliere, chief political strategist at Potomac Research Group.


A framework deal spelling out tax revenue and spending cut targets to be finalized in the new year could be possible, Valliere said.


“Boehner’s offer to allow tax rates to go up for taxpayers earning over $ 1 million fundamentally transforms fiscal cliff negotiations,” added Sean West, U.S. policy analyst at Eurasia Group, a political risk consultancy.


In a note to clients, West wrote that it signals, significantly, that Boehner ultimately believes a deal to avoid the cliff is still possible.


“The political burden is now shifted back to the president, who must be willing to take on his party in order to get a deal Boehner can ultimately pass. We do not think the president will overreach: Obama will work with Boehner to get to a deal.”


There are still several critical elements to a deal besides a tax rate increase on the wealthy, including Republican demands to cut spending on social programs.


Changes to the expensive Medicare and Medicaid health care programs for the elderly and the poor could be central to any deal, which must also include an increase in the federal debt limit needed by the end of February.


DEMANDS SOCIAL PROGRAM CUTS


Boehner conditioned his tax rate increase offer on Obama’s agreement to cuts in social program spending, often called entitlements.


Many Republican lawmakers want to raise the eligibility age for Medicare to 67 from 65. They also want to link Medicare to the income of recipients, making wealthier retirees pay more for their care.


Currently, Medicare does have some means testing, charging higher premiums for coverage of doctors visits and prescription drugs to individuals earning more than $ 85,000 and married couples earning more than $ 170,000. Only about 5 percent of recipients pay these higher premiums.


Thus far, Obama has offered only about $ 400 billion in 10-year entitlement savings, mostly through small adjustments in reining in health care costs – not fundamental changes such as raising the eligibility age.


And just as Boehner faces opposition in his own party to raising any tax rates, Obama faces opposition to cuts to Medicare, Medicaid and Social Security from Democrats, who pledged in election campaigns they would protect these programs.


A major bloc of congressional Democrats has already signaled they will not accept major cutbacks in Medicare as part of any fiscal cliff deal.


House Minority Leader Nancy Pelosi of California and Maryland Representative Chris Van Hollen of Maryland are among the high ranking Democrats in the House who have come out forcefully in recent days against raising the age for eligibility for Medicare to 67 years of age.


“Given the level of savings that is being talked about from Medicare, you can’t get it all from providers and drug makers,” said Paul Heldman, an analyst at Potomac Research, which tracks Washington policy for investors.


“So opponents of raising the eligibility age have reason to believe beneficiaries will take some sort of hit if a mega-deal is cut,” he said.


If Republicans are not successful in securing entitlement program cuts in exchange for a tax-rate increase on the wealthy, they are adamant about using a debt-limit increase as leverage to overhaul Social Security and Medicare.


The U.S. Treasury expects to reach its $ 16.4 trillion statutory debt cap by year-end, and will exhaust its remaining borrowing capacity around mid-February, risking a potential default.


Louisiana Republican Representative John Fleming, a member of the conservative Tea Party caucus who has never voted to increase the debt ceiling, said he would support a debt limit hike if it were part of a deal to make Medicare and Social Security sustainable.


The pace of activity could pick up the coming week.


House Republicans were told to prepare for a possible weekend session next week, potentially interrupting travel plans for the long Christmas holiday weekend.


House Majority Leader Eric Cantor scheduled “possible legislation related to expiring provisions of law,” a reference to the expiring tax cuts, for the end of the week, portending a weekend session. Cantor has said the House would meet through the Christmas holidays and beyond.


(This story was fixed to correct current top tax rate to 35 percent from 36 percent)


(Additional reporting by Thomas Ferraro, Richard Cowan and Kim Dixon; Editing by Fred Barbash, Todd Eastham and Jackie Frank)


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Obama: ‘We can’t tolerate this anymore’



President Barack Obama assured the grieving, shell-shocked Newtown community on Sunday that "you are not alone" and vowed sternly to wield "whatever power this office holds" in a quest to prevent future mass shootings.


"We can't tolerate this anymore," Obama said from behind a podium on the stage of a Newton High School auditorium, as adults wept, or hugged, or sat quietly, many hugging small children. "These tragedies must end. And to end them, we must change."


"In the coming weeks, I'll use whatever power this office holds to engage my fellow citizens -- from law enforcement, to mental health professionals, to parents, and educators -- in an effort aimed at preventing more tragedies like this, because what choice do we have?"he said.


The speech, broadcast nationwide, offered the bold suggestion that Obama might engage lawmakers on the subject of gun control -- a topic that has not been among his top priorities during his presidency.


"We can't accept events like this as routine. Are we really prepared to say that we're powerless in the face of such carnage?" Obama said.  That the politics are too hard? Are we prepared to say that such violence visited on our children year, after year, after year is somehow the price of our freedom?"


There were sobs from the crowd as the president read the first names of the 20 children slaughtered at Sandy Hook Elementary School on Friday and paid tribute to the six adults who died defending them. Twenty-six candles in twenty-six shining glass vases shone from the base of the podium.


Obama anticipated — and dismissed — some of the time-honored arguments against stricter restrictions on guns. "We will be told that the causes of such violence are complex, and that is true," he said. "No single law no set of laws can eliminate evil from the world or prevent every senseless act of violence in our society."


"But that can't be an excuse for inaction. Surely we can do better than this," he said. 


Across the country, people grieved for the 20 children — six and seven years old — and six adults killed in one of the worst mass shootings in America's history.


In Newtown and elsewhere, mourners gently piled notes, stuffed animals and American flags, balloons and flowers, in makeshift memorials where candles fluttered.


New York Giants wide receiver Victor Cruz played wearing a shoe that read "R.I.P. Jack Pinto" in black marker, an homage to a child slain in the massacre. Flags from coast to coast flew at half-staff. As the president's motorcade climbed the hill up the school, he could glimpse a few homes with Christmas lights -- but most were dark.


"Here in Newtown, I come to offer the love and prayers of a nation," the president said. "I am very mindful that mere words cannot match the depths of your sorrow, nor can they heal your wounded hearts."


"I can only hope it helps for you to know you are not alone in your grief that our world too has been torn apart. That all across this land of ours, we have wept with you. We've pulled our children tight," Obama said. "And you must know that whatever measure of comfort we can provide, we will provide. Whatever portion of sadness that we can share with you to ease this heavy load, we will gladly bear it."


In the auditorium where the president spoke, the audience included a large number of elementary school-age children, some carrying cuddly toys like teddy bears, according to pool reporter Stephen Collinson of Agence France-Presse.


Before the service, Obama met privately for more than an hour with families of the victims and emergency workers who responded to the crisis. As those workers entered the auditorium, the crowd erupted in a standing ovation. Some traded long hugs with members of the audience.


"We needed this. We needed to be together," said Rev. Matt Crebbin, the senior minister at Newtown Congregational Church. "These darkest days of our community shall not be the final word heard from us."


Connecticut Governor Dannel Malloy, describing his meeting with Obama, said that the president had called Friday "the most difficult day of  his presidency."



By 4 p.m., the line cars trying to reach the interfaith vigil stretched more than 2 miles from Newtown High School back through Sandy Hook -- and its growing makeshift memorial -- to Saint Rose church, the site of several vigils for (and hoax threats related to) Friday's massacre.

In Sandy Hook center, a lawn displayed lights with the phrase "FAITH. HOPE. LOVE." Across the street, a sign wrapped around a street lamp read, "Heaven must have been short on 27 angels."



The president spoke about the shooting on Friday,  his voice choked with emotion, one finger wiping away tears as they welled up. He vowed to "take meaningful action, regardless of the politics" to try to prevent future such tragedies. But hours before,  White House press secretary Jay Carney had decreed that "today's not the day" to discuss possible gun control measures.


The Obama administration has reportedly considered new gun restrictions in the past, only to shelve them.


The White House has shied from seeking tough new action from Congress — where new restrictions on gun purchases would likely run into stiff Republican opposition.


Obama's speech was the fourth in his presidency to memorialize a mass shooting. After the January 2011 rampage in Tucson, AZ, where then-Rep. Gabrielle Giffords was critically injured, the president spoke at a memorial for the six people killed, including Christina Taylor Green, 9.


Dylan Stableford contributed from Newtown



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